{"id":103798,"date":"2017-12-25T12:01:00","date_gmt":"2017-12-25T12:01:00","guid":{"rendered":"https:\/\/www.transcend.org\/tms\/?p=103798"},"modified":"2017-12-23T17:52:23","modified_gmt":"2017-12-23T17:52:23","slug":"u-s-government-lifts-ban-on-making-viruses-more-deadly-and-transmissible","status":"publish","type":"post","link":"https:\/\/www.transcend.org\/tms\/2017\/12\/u-s-government-lifts-ban-on-making-viruses-more-deadly-and-transmissible\/","title":{"rendered":"U.S. Government Lifts Ban on Making Viruses More Deadly and Transmissible"},"content":{"rendered":"<blockquote><p><em>Like a horror movie prologue.<\/em><\/p><\/blockquote>\n<div id=\"attachment_103799\" style=\"width: 510px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus2.jpg\" ><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-103799\" class=\"wp-image-103799\" src=\"https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus2-1024x512.jpg\" alt=\"\" width=\"500\" height=\"250\" srcset=\"https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus2-1024x512.jpg 1024w, https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus2-300x150.jpg 300w, https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus2-768x384.jpg 768w, https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus2.jpg 1200w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><\/a><p id=\"caption-attachment-103799\" class=\"wp-caption-text\">Colorized scanning electron micrograph of filamentous Ebola virus particles (blue). NIAID \/ Flickr<\/p><\/div>\n<p><em>21 Dec 2017 &#8211; <\/em>Some horror movie tropes just come off as unbelievable, they\u2019re so ridiculous and overused. Like, \u201cGirl who falls down for no apparent reason while being chased by a killer.&#8221; Or, \u201cGroup of friends that decides to split up when it\u2019s obvious being alone will get you murdered.&#8221; And then there&#8217;s this one: \u201cScience laboratory creates horrible disease that will inevitably escape and kill all of humanity,\u201d which might be the most unbelievable, since it defies both logic and actual laws. Or rather, it did until Tuesday [19 Dec], when the U.S. government announced it was lifting a three-year <a target=\"_blank\" href=\"https:\/\/www.nytimes.com\/2017\/12\/19\/health\/lethal-viruses-nih.html?_r=0\" >ban on federal funding for experiments that alter viruses<\/a> to make them even deadlier.<\/p>\n<p>\u201cGain-of-function\u201d research, in which scientists make pathogens more powerful or easily transmissible, is aimed at preventing disease outbreaks by better understanding how they might occur. The studies allow scientists, working in a highly controlled environment, to learn how a flu virus might mutate into a superbug capable of killing millions\u2014a sort of game of wits played to gain insight into nature\u2019s unpredictability. The ultimate goal is to proactively create vaccines, medications and other solutions to stop contagion in its tracks.<\/p>\n<p>The new National Institutes of Health policy reverses a 2014 Obama administration funding ban on gain-of-function research projects specifically involving all forms of the influenza virus, Middle East respiratory syndrome (MERS), and severe acute respiratory syndrome (SARS). The new rules would extend beyond those viruses, \u201c<a target=\"_blank\" href=\"https:\/\/www.nytimes.com\/2017\/12\/19\/health\/lethal-viruses-nih.html?_r=0\" >apply[ing] to any pathogen that could potentially cause a pandemic<\/a>,\u201d according to the New York Times. \u201cFor example, they would apply to a request to create an Ebola virus transmissible through the air.\u201d<\/p>\n<p>Possibly aware that this sounds like the prologue to a very hacky horror movie, the NIH accompanied its announcement with a list of criteria that proposals must meet before funding will be granted. According to those terms, a panel will only greenlight projects if the work promises to yield practical solutions, such as an effective antiviral treatment; the research benefits must sufficiently outweigh the risks; and researchers must prove their experiment outcomes cannot be obtained using safer methodologies. Contenders will also have to prove their researchers and facilities \u201c<a target=\"_blank\" href=\"https:\/\/www.cidrap.umn.edu\/news-perspective\/2017\/12\/feds-lift-gain-function-research-pause-offer-guidance\" >have the capacity to do the work safety and securely<\/a> and to respond rapidly if there are any accidents, protocol lapses, or security breaches.\u201d<\/p>\n<div id=\"attachment_103800\" style=\"width: 320px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus.jpg\" ><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-103800\" class=\"size-full wp-image-103800\" src=\"https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus.jpg\" alt=\"\" width=\"310\" height=\"310\" srcset=\"https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus.jpg 310w, https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus-150x150.jpg 150w, https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus-300x300.jpg 300w\" sizes=\"auto, (max-width: 310px) 100vw, 310px\" \/><\/a><p id=\"caption-attachment-103800\" class=\"wp-caption-text\">Photo Credit: Shutterstock \/ Lightspring<\/p><\/div>\n<p>\u201cWe have a responsibility to ensure that research with infectious agents is conducted responsibly, and that we consider the potential biosafety and biosecurity risks associated with such research,\u201d NIH director <a target=\"_blank\" href=\"https:\/\/www.nih.gov\/about-nih\/who-we-are\/nih-director\/statements\/nih-lifts-funding-pause-gain-function-research\" >Francis S. Collins said in a statement<\/a>. \u201cI am confident that the thoughtful review process&#8230;will help to facilitate the safe, secure, and responsible conduct of this type of research in a manner that maximizes the benefits to public health.\u201d<\/p>\n<p>Despite those reassurances, critics continue to express concern about potential mishaps. There\u2019s some precedent for this. In 2014, CNN reported that <a target=\"_blank\" href=\"https:\/\/www.cnn.com\/2014\/07\/15\/health\/cdc-anthrax-ziploc-bags\/index.html\" >dozens of workers at the CDC had been accidentally exposed to anthrax<\/a>, while others had mishandled samples of the bacteria. No staff were found to be infected by the disease after prolonged monitoring. A Vice Motherboard <a target=\"_blank\" href=\"https:\/\/motherboard.vice.com\/en_us\/article\/d34vyj\/the-us-will-fund-research-to-make-pathogens-deadlier-again\" >report notes that between<\/a> \u201c2003 and 2009, <a target=\"_blank\" href=\"https:\/\/www.cidrap.umn.edu\/news-perspective\/2011\/09\/report-395-mishaps-us-labs-risked-releasing-select-agents\" >there were 395 events reported<\/a> that could have resulted in exposure to toxic agents, although this resulted in just seven infections.\u201d<\/p>\n<p>Harvard epidemiologist Marc Lipsitch offered tepid support, telling the Times the approval panels are &#8220;a small step forward,\u201d but cautioning that gain-of-function experiments \u201chave given us some modest scientific knowledge and done almost nothing to improve our preparedness for pandemics, and yet risked creating an accidental pandemic.\u201d<\/p>\n<p>Conversely, Stony Brook University president and biomedical researcher Samuel Stanley worries that the NIH decision, after three years of funding prohibition in this area, may be too little and just a wee bit too late.<\/p>\n<p>&#8220;There has been increased scrutiny of laboratories working in this area, which can lead to an even more robust culture of safety,\u201d Stanley told NPR. \u201cBut I also fear that the moratorium may have delayed vital research. That could have long lasting effects on the field. <a target=\"_blank\" href=\"https:\/\/www.npr.org\/sections\/health-shots\/2017\/12\/19\/571744856\/nih-lifts-ban-on-research-that-could-make-deadly-viruses-stronger\" >I believe nature is the ultimate bioterrorist<\/a> and we need to do all we can to stay one step ahead.&#8221;<\/p>\n<div id=\"attachment_103801\" style=\"width: 610px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus3.jpg\" ><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-103801\" class=\"wp-image-103801\" src=\"https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus3.jpg\" alt=\"\" width=\"600\" height=\"402\" srcset=\"https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus3.jpg 800w, https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus3-300x201.jpg 300w, https:\/\/www.transcend.org\/tms\/wp-content\/uploads\/2017\/12\/disease-virus3-768x515.jpg 768w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><p id=\"caption-attachment-103801\" class=\"wp-caption-text\">Health workers killed chickens in a Hong Kong market in 2014 in an effort to stop the spread of H7N9 flu. It&#8217;s being watched closely as a virus that might spark a pandemic outbreak.<br \/> Vincent Yu\/AP<\/p><\/div>\n<p>_____________________________________<\/p>\n<p style=\"padding-left: 30px;\"><em>Kali\u00a0Holloway is a senior writer and the associate editor of media and culture at <\/em>AlterNet.<\/p>\n<p><a target=\"_blank\" href=\"https:\/\/www.alternet.org\/personal-health\/us-government-lifts-ban-making-viruses-more-deadly-and-transmissible\" >Go to Original \u2013 alternet.org<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>21 Dec 2017 &#8211; Like a horror movie prologue.<\/p>\n","protected":false},"author":4,"featured_media":103799,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[52],"tags":[],"class_list":["post-103798","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"_links":{"self":[{"href":"https:\/\/www.transcend.org\/tms\/wp-json\/wp\/v2\/posts\/103798","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.transcend.org\/tms\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.transcend.org\/tms\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.transcend.org\/tms\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.transcend.org\/tms\/wp-json\/wp\/v2\/comments?post=103798"}],"version-history":[{"count":0,"href":"https:\/\/www.transcend.org\/tms\/wp-json\/wp\/v2\/posts\/103798\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.transcend.org\/tms\/wp-json\/wp\/v2\/media\/103799"}],"wp:attachment":[{"href":"https:\/\/www.transcend.org\/tms\/wp-json\/wp\/v2\/media?parent=103798"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.transcend.org\/tms\/wp-json\/wp\/v2\/categories?post=103798"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.transcend.org\/tms\/wp-json\/wp\/v2\/tags?post=103798"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}